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Popular Articles

Maternal Immunity Not All Good For A Fetus
As a fetus does not mount an immune response to maternal proteins that cross the placenta, it has been assumed that a fetus would not reject non-genetically matched blood cells (specifically allogeneic blood cells) if they were transplanted while the fetus was in utero. The hope is that this procedure, which is known as IUHCT, could provide a viable approach for treating congenital blood disorders. However, studies using a mouse model of IUHCT indicate that most fetal recipients of allogeneic blood cells lose their transplanted cells 3-5 weeks after transplantation. Alan Flake and colleagues, at Children"s Hospital of Philadelphia, have now identified an immune mechanism responsible for graft failure in this model of IUHCT. Surprisingly, although fetal immune cells eliminated the transplanted allogeneic blood cells, they were triggered to do so by immune molecules known as alloantibodies that they obtained from their mother"s breast milk. The maternal alloantibodies were produced in response to IUHCT and so the authors conclude that in the absence of either a maternal immune response or transmission of the maternal alloantibodies to the fetus, transplanted blood cells should not be rejected, leaving open the door for IUHCT as a potential clinical strategy.

Analysis Of Four Large Post-Marketing Surveillance Studies Describe Clinical Effects Of Sucrose-Formulated Recombinant Factor VIII
New data pooled from four large, "real world" post-marketing surveillance studies showed that sucrose-formulated recombinant factor VIII (rFVIII-FS) reduced bleeding and provided data regarding adverse events in more than 950 patients with mild-to-severe hemophilia A. Additionally, rates of inhibitor formation were reported in both previously treated and previously untreated patients. The data were presented at the XXII Congress of the International Society on Thrombosis and Haemostasis (ISTH).(1)(2)
News of the day
New Book: Does Quantum Mechanics Show A Connection Between The Human Mind And The Cosmos?
Does quantum mechanics show a connection between the human mind and the cosmos? Are our brains tuned into a "cosmic consciousness" that pervades the universe enabling us to make our own reality? Do quantum mechanics and chaos theory provide a place for God to act in the world without violating natural laws?
Diagnostics

Embarrassment Leads To Taking Health Risks

A shocking 1 in 10 people say they have had unprotected sex because they were too embarrassed to buy condoms from a pharmacy. This disconcerting statistic is the finding of latest research by new online pharmacy http://www.mastersdirect.com, revealing people"s opinions about their most embarrassing health problems. Furthermore almost 50% of the population has suffered a health problem like thrush in silence rather than face the embarrassment of seeking medical attention and a quarter has simply walked out of a pharmacy because they were too embarrassed to ask for a particular health product. The results revealed that the high street pharmacy can be a "humiliation hot-spot" for people confronting their embarrassing health issues. The most toe-curlingly embarrassing products were voted to be: condoms, incontinence pants and personal lubricants. Thrush creams, tampons and pregnancy tests also made people feel conspicuous. In an attempt to hide their embarrassment over their purchases, well over a third had even bought something they didn"t need as a "cover-up". The results come as global healthcare company Masters Pharmaceuticals launch a new online pharmacy, fully registered by the RSPGB - and regulated by the NHS . Founded on 25 years" experience distributing pharmacy products worldwide, www.mastersdirect.com offers customers the services of a high street pharmacy but with the added convenience and privacy of ordering and receiving products at their home. Customers who would like to privately discuss their health issue with a professional can speak to a registered pharmacist by telephone or on email. Media doctor Dr Dawn Harper, who welcomes the launch of the website, said, "Pharmacies have come a long way in offering health care to the public but this research highlights how some people still feel awkward about openly discussing their private health issues. The big worry is that embarrassment could put their health at risk. I have always advised against randomly buying medication on the internet but with a professional online pharmacy like http://www.mastersdirect.com patients can feel reassured that they are ordering genuine medication directly to their door from the privacy and convenience of home" Masters Direct


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