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Newborn Brain Cells Show The Way
Although the fact that we generate new brain cells throughout life is no longer disputed, their purpose has been the topic of much debate. Now, an international collaboration of researchers made a big leap forward in understanding what all these newborn neurons might actually do. Their study, published in the July 10, 2009, issue of the journal Science, illustrates how these young cells improve our ability to navigate our environment.

New Control System Of The Body Discovered - Important Modulator Of Immune Cell Entry Into The Brain - Perhaps New Target For The Therapy
Researchers in Berlin, Germany have ameliorated inflammation of the brain in mice caused by immune cells. A receptor they discovered on the surface of T cells in the central nervous system (CNS) plays the key role. The researchers showed that this bradykinin receptor 1 (B1) controls the infiltration of immune cells into the CNS. When they activated B1 in mice with encephalitis, they were able to slow down the crossing of the immune cells through the blood-brain-barrier into the CNS. As a result, the inflammation markedly decreased. The work by Dr. Ulf Schulze-Topphoff, Prof. Orhan Aktas, and Professor Frauke Zipp (Cecilie Vogt-Clinic, Charité - Universitätsmedizin Berlin, Max DelbrÃøck Center for Molecular Medicine (MDC) Berlin-Buch and NeuroCure Research Center) together with researchers in Canada and the USA may unveil a new target for the treatment of chronic inflammatory diseases such as multiple sclerosis (MS) (Nature Medicine, doi 10.1038/nm.1980)*.
News of the day
Under-Use Of Hospice Care By Many Terminally Ill Patients: Study
Hospice, a well-established approach to palliative care, has enabled countless people worldwide to die with dignity. Through focusing on the patient rather than the disease, individuals can spend the last weeks of their lives in an environment where hospice caregivers minimize their pain, maximize their comfort, and provide bereavement services for loved ones and family members.
Cardiovascular

First U.K. Stem Cell Awareness Rally To Take Place In Manchester, England On August 9th, 2009

In what will be the Stem Cell Awareness Association"s seventh awareness rally, past patients, interested physicians, and prospective patients will meet in Manchester to learn about stem cell technologies and discuss the various current treatments available throughout the world. Stem cell advocate Darren Clarke is organizing the Manchester event. Mr. Clarke became involved in stem cell advocacy early in his daughter, Dakota"s, life. At three years old, Dakota became the first child from Britain and Ireland to be treated for septo-optic dysplasia (SOD) in China. She was born blind but began to regain her vision just weeks into her stem cell treatment. Her parents have been passionate stem cell advocates ever since. Darren said, "I felt that western medical opinion directed people away from the treatments available to people with problems like Dakota"s. It"s my aim to let people see that there is an option out there. If I can spread the news that it works and that there is hope, then all the effort will be worthwhile." To read more about Dakota Clarke, details can be found on Dakota"s website. Peter Conry, a Dublin pharmacist and pharmaceutical industry veteran interested in stem cell technology, will be speaking at the event about how his work and travel throughout Asia transformed him from being a medically trained skeptic to informed stem cell advocate. Peter states, "I visited stem cell treatment facilities and spoke at length with patients and staff. I came away convinced I"d witnessed the start of a significant medical advance." Shel Morse, stem cell advocate and mother of Macie Morse, will be attending from Colorado to share the story of her daughter, Macie, who regained vision after stem cell treatment in China. Macie, at 15 years old, was denied a driver"s permit because optic nerve hypoplasia (ONH) had left her legally blind. After stem cell treatment in China, Macie returned to the States and one year later had the required vision to pass the test. Mrs. Morse said, "Because of what stem cells have done for my daughter, I am now on a mission to help bring awareness to as many people as possible. It"s time to empower the people to make informed choices based on what is really available out there." Also in attendance will be Luca Ricci from Shenzhen Beike Biotechnology, which provided the stem cells for Macie Morse"s treatment. Mr. Ricci will be speaking about current treatments offered and answering patient questions about the therapy process -- from initially contacting Beike to life in China to returning home. This U.K. rally will be the association"s first event held outside of the United States and will follow in the footsteps of previous events by creating a community where stem cell patients have the opportunity to share their experiences with prospective patients. It will also provide an opportunity for doctors and medical specialists to not only connect with patients but also consider how stem cell technology can be successfully applied not just overseas, but locally. All patients who are interested, who are considering stem cell treatments or who have already had stem cell treatments are welcome to join the U.K. Stem Cell Awareness Rally: ÷  Location: Manchester, England ÷  Place: The Thistle Manchester Hotel ÷  Date: August 9th, 2009 ÷  Time: 10 a.m. More information about the event can be found at the Stem Cell Awareness Association"s web site. Stem Cell Awareness Association


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