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Cardiologist Urges People To Get Informed About Angioplasty
A report broadcast during the CBS Evening News on June 8 noted that one in 200 patients die during elective coronary angioplasty procedures and suggested that patients may be safest at institutions where surgical backup is readily available when complications occur. The report also noted that as many as 40 percent of the angioplasties performed may be unnecessary because patients could experience the same benefits from drug therapies.

Brain Activity Stablilized By Dynamic Molecular Mechanism
In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. Here, the Japanese research group led by Professor Masaki Fukata, Drs. Yuko Fukata and Jun Noritake in National Institute for Physiological Sciences, Japan, found that two types of palmitoylating enzymes finely-tune the location and function of a major synaptic protein, PSD-95, in different ways. They also found that this mechanism contributes to keeping synaptic activity stable when synaptic activity dynamically changes. The Japan Science and Technology Agency (JST) supported this study. They report the finding in Journal of Cell Biology published on July 13, 2009.
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Nç©ovacs To Expand Clinical Testing Of Its TNF-alpha Kinoid Lead Product Candidate Following Positive Preliminary Findings From A Phase I/II Study
Neovacs, a biotechnology company developing proprietary immunotherapeutics for autoimmune and chronic diseases, announced that subject to regulatory consent, it plans to initiate a Phase II study of its TNF-alpha Kinoid later this year in rheumatoid arthritis patients who have failed treatment with at least one TNF-alpha inhibitor. The decision to proceed with the trial was based on an initial review of encouraging data from the company"s Phase I/II study in Crohn"s disease.
Endocrinology

New Data Say Uninsured Account For Nearly One-Fifth Of Emergency Room Visits

Health and Human Services Secretary Kathleen Sebelius today released new data from the Nationwide Emergency Department Sample -- the largest, all-payer emergency department database in the United States. The Nationwide Emergency Department Sample is designed to help public health experts, policymakers, health care administrators, researchers, journalists and others find the data they need to answer questions about care that occurs in U.S. hospital emergency departments. These data indicate that uninsured persons accounted for nearly one-fifth of the 120 million hospital-based emergency department visits in 2006. Low-income patients accounted for almost one-third, and residents of rural areas accounted for one-fifth of the visits. "Our health care system has forced too many uninsured, rural and low-income Americans to depend on the emergency room for the care they need," said Secretary Sebelius. "We cannot wait for reform that gives all Americans the high-quality, affordable care they need and helps prevent illnesses from turning into emergencies." The database is managed by HHS" Agency for Healthcare Research and Quality (AHRQ) and generates national estimates on the number of emergency department visits in all community hospitals, by region, urban/rural location, teaching status, ownership and trauma designation. It also provides in-depth information on acute management of patients for all visits, including why patients were seen in the emergency department, the treatments they received, what happened to them at the end of the visit (admitted to the hospital, discharged home, transferred to another hospital, died in the emergency room or left against medical advice), the charge for their care and who was billed. The Nationwide Emergency Department Sample contains 26 million records from emergency department visits from approximately 1,000 community hospitals nationwide. This represents 20 percent of all U.S. hospital emergency departments. The database also provides weighted calculations for national estimates of the 120 million ED visits in 2006. "AHRQ has a long history of supporting health services research related to emergency medicine, and the richness of these new data will increase our capacity for research and decision making," said AHRQ Director Carolyn M. Clancy, M.D. "The new database will give emergency planners and other policymakers the data they need to help improve the quality, safety and effectiveness of emergency medical care." AHRQ also released its latest Nationwide Inpatient Sample - the largest, most powerful database on hospital care in the United States, covering all patients, regardless of their type of insurance or whether they were insured. The 2007 Nationwide Inpatient Sample provides users with an in-depth look at why patients were hospitalized, the treatments and procedures they received and what happened to them at discharge. Researchers can use the Nationwide Inpatient Sample to examine trend data as far back as 1988. The 2007 Nationwide Inpatient Sample is based on discharge data from 8 million hospital stays at more than 1,000 community hospitals. The two databases, as well as the 2006 Kids" Inpatient Database on pediatric inpatient care, are part of AHRQ"s Healthcare Cost and Utilization Project (HCUP), a federal-state-industry partnership for building a standardized, multi-state health data system. In addition to databases, HCUP includes software tools and statistical reports to inform policymakers, health system leaders, researchers and the public. U.S. Department of Health and Human Services


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