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Endocrine Society Unveils First-Ever Scientific Statement
Endocrine Society Unveils First-Ever Scientific Statement: Inaugural Statement Identifies Endocrine-Disrupting Chemicals as a Significant Concern to Public Health

UK's NICE Recommends Use Of Erbitux For Metastatic Colorectal Cancer Patients
The United Kingdom"s National Institute for Health and Clinical Excellence (NICE) has published a Final Appraisal Determination (FAD) recommending the use of the drug Erbitux® (cetuximab) in combination with chemotherapy as a 1st-line treatment for patients with metastatic (advanced) colorectal cancer (mCRC) who have met specific additional criteria1 - presenting the possibility of potentially curative surgery.2 The treatment is recommended for patients in whom the cancer has spread only to the liver and who have normal or "wild-type" KRAS tumors.1 In the UK, a recommendation by NICE is a prerequisite for funding of a medical treatment by the National Health Service.
News of the day
IMPACT Study Showed Longer Valcyte(R) (valganciclovir Hydrochloride Tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV)
New Phase III study results presented for the first time at the ninth annual American Transplant Congress 2009 (ATC) demonstrate that doubling the duration of preventive therapy ("prophylaxis") with Valcyte (oral valganciclovir) significantly reduced the incidence of CMV disease by 56% in high-risk kidney transplant patients within the first year post-transplant.
Sexual Health

Use Of Adipose Stem Cells And Polylactide Discs For Tissue Engineering Of The Temporomandibular Joint Disc

There is currently no suitable replacement for the irreversibly damaged temporomandibular joint (TMJ) discs after discectomy. In this study, we designed a TMJ disc shaped scaffold of biodegradable polylactide and combined it with adipose stem cells (ASCs). The expression of the extracellular matrix components, typical for the normal TMJ disc, was induced in the ASC-seeded PLA discs in chondrogenic medium. The expression was close to similar to conventional pellet cultures but still remained from that measured in the positive control tissue. The combination of ASCs and PLA discs has potential for the development of a tissue-engineered TMJ disc replacement. Journal of the Royal Society Interface


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