Mental Health
Living in an area with more fast food outlets and convenience stores than supermarkets and grocers has been associated with obesity in a Canadian study. Researchers writing in the open access journal BMC Public Health have shown that your local food environment can affect your weight.
Risk for hepatocellular carcinoma, a primary malignancy of the liver, was statistically significantly higher among women with hepatitis B virus (HBV) infection than among women without the virus, according to a study published online June 17 in the JNCI.
Patients treated for Hodgkin lymphoma with radiation therapy have a substantially higher risk of stroke, according to a new study published June 17 online in the Journal of the National Cancer Institute.
Clinuvel Pharmaceuticals Limited (ASX: CUV; XETRA-DAX: UR9; ADR: CLVLY) is pleased to announce that afamelanotide, its photoprotective drug, has been granted Orphan Medicinal Product (OMP) designation by the European Medicines Agency (EMEA) for the treatment of Solar Urticaria (SU). The EMEA granted afamelanotide its first OMP designation in March 2008 for the treatment of Erythropoietic Protoporphyria (EPP), Clinuvel"s lead indication currently in Phase III clinical trials.
The Partnership to Fight Chronic Disease (PFCD) held a Capitol Hill briefing to discuss comprehensive state health care reform efforts, why some succeeded and others failed, and why focusing on reducing the burden of chronic disease should be at the center of our national effort to reform health care.
U.S. Representatives Rep. Artur Davis (D-AL), Steve Israel (D-NY) and Mary Jo Kilroy (D-OH) have introduced H.R. 2872, the Medicare Quality Cancer Care Demonstration Act of 2009. H.R. 2872 is a bill that will authorize Congress to direct the Centers for Medicare & Medicaid Services (CMS) to implement the Quality Cancer Care Demonstration (QCCD) project.
An article published Online First and in the July edition of The Lancet Oncology reports that the combination of human papillomavirus (HPV) testing with regular liquid-based cytology (LBC) screening does not improve the detection of cervical cancer compared with LBC screening alone.
George Dahlman, senior vice president of public policy for The Leukemia & Lymphoma Society (LLS), testified today before the U.S. Senate Subcommittee on Defense Appropriations, calling for funding for a dedicated, stand-alone blood cancer research program at the Department of Defense (DoD).
The College of Optometrists in Vision Development (COVD) is launching their annual campaign to educate the public on the steps they can take to ensure their children aren"t struggling with reading and learning because of undiagnosed vision problems.
The American Institute for Cancer Research (AICR) is launching a new campaign in partnership with Giant Food. The campaign, called Shop for Health, Eat for Life, will run in all Giant food stores from June 19 to July 2, 2009.
The American Pharmacists Association (APhA) applauds the recommendations regarding chronic disease in the report by the Bipartisan Policy Center"s (BPC) Leaders" Project, entitled "Crossing Our Lines: Working Together to Reform the U.S. Health System." The report outlines key health care reform policy recommendations from a bipartisan perspective to ensure that all Americans have quality, affordable health care.
Roche Applied Science announced the availability of a new detection kit for the Influenza A/H1N1 virus. The detection kit is offered for use in life science research. Roche currently is filing to get approval of the local health authorities worldwide for use of the kit in emergency situations.
Poor egg handling practices in restaurants and takeaways could be putting UK consumers at risk, reveals a new report from the Health Protection Agency and LACORS (Local Authorities Coordinators of Regulatory Services).
A series of new polls this week show support for major health care reform, but trepidation about certain policy proposals, and anxiety about quickly growing health care costs, the possibility of losing coverage, and the federal budget deficit in general.
"Employers who offer health insurance coverage could see a 9 percent cost increase next year, and their workers may face an even bigger hit, according to a report Thursday from consulting firm PricewaterhouseCoopers," the Associated Press reports. Workers concerned about losing their jobs" and their insurance, while it lasts - are using more health care than usual, contributing to rising costs, the report says. As the costs increase, employers are also likely to shift more of the burden to employees. "A total of 42% of employers surveyed said they would increase employees" share of costs," the AP reports.
The GOP Can Stop ObamaCare Wall Street Journal
Administrators, faculty and staff are making considerable progress toward the opening of the Oakland University William Beaumont School of Medicine, which plans to begin accepting student applications in 2010 pending accreditation by the Liaison Committee for Medical Education.
Rural Solutions, an organization in northeast Colorado, held the "Community HIV/AIDS Education and Action Conference" as part of its ongoing effort to address issues related to HIV, the Sterling Journal-Advocate reports. At the conference, the organization presented the results of a recent needs assessment of HIV/AIDS services in the northeastern part of the state - conducted in partnership with the Center for Research Strategies and funded through the Colorado Department of Public Health and Environment - which found that HIV prevention services in the area are limited; barriers exist for HIV testing including confidentiality and costs; and mental health and substance use services for at-risk people also are limited, according to the Journal-Advocate (Jones, Sterling Journal-Advocate, 6/17).
There may be thousands of things large and small that can be done to better control pollution on even the smallest waterways, and a new tool developed at Purdue University may help sort out how to choose the best ones.
The National Infertility Awareness Campaign (NIAC) welcomed the document "Standardising Access Criteria to NHS Fertility Treatment"1 produced by Infertility Network UK (I N UK) and funded by the Department of Health.
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Having partnered last year with an international team that surveyed the genomes of 12,000 individuals to find a genetic cause for gout, Johns Hopkins scientists now have shown that the malfunctioning gene they helped uncover can lead to high concentrations of blood urate that forms crystals in joint tissue, causing inflammation and pain - the hallmark of this disease.
Southampton researchers studying the treatment of severe asthma have won a share of a 23m euro grant. Experts at the city"s Respiratory Biomedical Research Unit (BRU), based at Southampton General Hospital, are among a consortium of 14 European academic centres of excellence to receive a slice of the funding.
A new survey completed by the British Association of Aesthetic Plastic Surgery (BAAPS) suggests that patients may experience higher complication rates with permanent cosmetic fillers than with other types of cosmetic injections. The survey reveals 38.5% of surgeons saw 1-3 patients over the past year experiencing complications with permanent facial fillers, and 23% of surgeons saw 1-3 patients in the past year with complications so severe surgery was needed to treat those complications. "Permanent fillers present challenges, particularly for inexperienced injectors," says Coalition leader Julius Few, MD, a plastic surgeon practicing in Chicago, IL. "In addition to potential complications that may develop years after injection, the challenge of a permanent, synthetic filler is the anticipation of aging changes and the need for outcomes that will not look unnatural over time. To date, fat continues to be the option closest to a permanent filler with a proven safety record."
The amount of time imaging equipment is in use in outpatient settings does not approach use rates President Obama and the Medicare Payment Advisory Commission (MedPAC) recommend Medicare utilize to calculate reimbursement for imaging, according to data recently collected by the Radiology Business Management Association (RBMA), a national association of business professionals in radiology.
China Aoxing Pharmaceutical Company, Inc. (OTCBB: CAXG) ("China Aoxing"), a pharmaceutical company specializing in research, development, manufacturing and marketing of narcotic and pain-management products, announced that it has completed the registration trial with Codeine Phosphate, a compound oral solution for the treatment of acute moderate to severe cough. Top-line results from this trial are expected to be announced by the end of the third quarter of 2009.
Well-heeled donors, private corporations and average citizens sending money to their favorite charities are changing the landscape of global health funding, according to a new study by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.
Studies performed in three animal models confirmed the safety and intensive immunogenicity of a new type of intranasal H5N1 influenza vaccine, according to the latest preclinical study data announced today by the Vienna based firm, Avir Green Hills Biotechnology. The study data was just published in PloS One, the Public Library of Science.
Researchers at the Max Planck Institute for Chemical Ecology in Jena and their colleagues from the Czech Academy of Sciences in Prague have developed a new method to quickly and reliably detect metabolites, such as sugars, fatty acids, amino acids and other organic substances from plant or animal tissue samples. One drop of blood -- less than one micro liter -- is sufficient to identify certain blood related metabolites.
New evidence underscores the theory of human origin that suggests humans most likely share a common ancestor with orangutans, according to research from the University of Pittsburgh and the Buffalo Museum of Science. Reporting in the June 18 edition of the Journal of Biogeography, the researchers reject as "problematic" the popular suggestion, based on DNA analysis, that humans are most closely related to chimpanzees, which they maintain is not supported by fossil evidence.
A study by Oregon State University researchers suggests that school-based prevention programs begun in elementary school can significantly reduce problem behaviors in students.
Cephalon, Inc. (Nasdaq: CEPH) announced results from a pivotal clinical trial of lestaurtinib (CEP-701) in patients with relapsed acute myelogenous leukemia (AML) expressing FLT3 activating mutations. The study was designed to show the benefit of lestaurtinib in this patient population when given in sequence with standard induction chemotherapy compared to those treated with standard induction chemotherapy alone. An analysis of the study showed that patients who were treated with lestaurtinib showed similar rates of complete response but no increased benefit in overall survival, compared to those who received induction chemotherapy alone.
A study of the award-winning Behavioral Pharmacy Management Program (BPM) shows the private-public Medicaid partnership program has helped improve patient care while saving eight states almost $95 million in behavioral health pharmaceutical costs. Lilly funds the program, which is designed and run by research firm Comprehensive NeuroScience, Inc. (CNS) at the sole direction and guidance of state Medicaid departments. The BPM, which has been executed in more than half of the states, has won a variety of national awards, including the Substance Abuse and Mental Health Services Administration Science and Service Award, URAC Silver Award for Best Practices in Consumer Empowerment and Protection, American Psychiatric Association Bronze Achievement Award and Disease Management Association of America Gold Award.
TranSenda International, LLC announced today that it is developing a new solution, Cortex, designed to improve an organization"s ability to manage a clinical trial"s performance. Based upon patent-pending ClinBUS® data interchange technology already in use in TranSenda"s Office-Smart solutions, Cortex will enable organizations to leverage the power of access to centralized operational data from all applications used across all clinical studies. For years the industry has struggled with an increasingly fragmented environment of disconnected clinical applications, sites and partners. TranSenda"s Cortex, with its proven ClinBUS technology, represents a breakthrough in managing and controlling studies within a common environment-independent of study data formats and clinical trial applications.
Using virtual reality simulators to train surgeons improves performance and reduces operating time, finds a study published on bmj.com today.
The Actuarial Profession has published, for consultation, a prototype model to project future mortality rates. The model has been developed in response to the continuation of significant increases in life expectancy since projections were last published by the Profession in 2002.
New plans to improve the support and care for individuals and their families living with dementia were announced by Health Minister Edwina Hart.
UroToday.com - Insufficient intake of zinc (Zn) can impair antioxidant defenses and may be an important risk factor in oxidant release, compromising the mechanism of DNA repair, and making the sperm cell highly susceptible to oxidative damage. In the absence of Zn, the possibility of increased oxidative damage exists that would contribute to poor sperm quality. Infertile men and men who smoke are very susceptible to oxidative damage induced by free radicals. In the present study, we hypothesized that major changes in the level of seminal Zn levels are related with low quality of sperm and poor fertilizing capacity.
Indiana University School of Medicine researchers have developed a new breast cancer diagnostic marker that could enable physicians to more easily determine which patients have a less aggressive form of the disease that may not require chemotherapy treatment.
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Responding to the publication of the Public Accounts Committee report, NHS pay modernisation in England: Agenda for Change, Dr Peter Carter, RCN Chief Executive & General Secretary, said:
A Beth Israel Deaconess Medical Center project called "open notes"" will make doctor"s notes available to as many as 35,000 patients online along with the rest of their medical records for a year, the Boston Globe reports.
Just in time for Father"s Day weekend, the Secretary of Health and Human Services Kathleen Sebelius announced a new public service campaign today promoting fatherhood that features a PSA by President Obama. The campaign, sponsored by the department"s Administration for Children and Families and the Advertising Council, can be found at http://www.fatherhood.gov. The public service announcements and supporting campaign materials highlight the critical role fathers play in their children"s lives.
AIDS Re Center of Wisconsin Chief Operating Officer Mike Gifford said that Wisconsin has the lowest AIDS death rate in the nation, WPR News reports. Gifford said that CDC data indicate that Wisconsin and Minnesota have one AIDS death annually for every 100,000 people. He credits a strong system of health care professionals and state and private support for the low death rate, but noted that hundreds of people living with HIV in Wisconsin are not getting the services they need (Simonson, WPR News, 6/18).
The number of Filipino "women who die yearly due to childbirth and pregnancy complications has doubled in the last four years," and a reproductive health bill opposed by some lawmakers and stalled in Congress could address this rise in maternal mortality, health groups say, ABS-CBN News reports. The bill includes a "range of programs to promote reproductive health through education and access" to family planning methods, according to ABS-CBN News.
As summer pests are a natural part of the outdoors and typically viewed simply as a nuisance, many believe that they have a full understanding of the risks associated with such. Yet, the National Pest Management Association (NPMA) warns that there are a multitude of myths about summer insects that homeowners subscribe to - most of which wrongly minimize the threats of stinging insects, mosquitoes and ants.
Senate Democratic leaders on Thursday circulated talking points stating that Supreme Court nominee Sonia Sotomayor has a "mainstream record of judicial modesty," the AP/Miami Herald reports. The document includes a quote from Sotomayor expressing her belief in basing judicial decisions on the Constitution rather than on politics.Meanwhile, Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) and ranking member Jeff Sessions (R-Ala.) also wrote to the president of LatinoJustice PRLDEF, formerly known as the Puerto Rican Legal Defense and Educational Fund, requesting the quick disclosure of documents Sotomayor has requested in relation to her work with the group (Hirschfeld Davis, AP/Miami Herald, 6/19). Sotomayor worked with the group from 1980 to 1992, assisting in a number of legal briefs and helping the group develop stances on public policy matters (Stanton, Roll Call, 6/18). According to the AP/Herald, interest groups and members of both political parties are "competing to define" Sotomayor ahead of her confirmation hearing, which is scheduled to begin July 13. Conservative groups have focused on labeling her an "activist" and singled out her involvement with PRLDEF as evidence of her support for abortion rights. The group sided with abortion-rights supporters in several major Supreme Court cases during Sotomayor"s time on its board (AP/Miami Herald, 6/19).
Researchers from the newly-established VGTI Florida and the University of Montreal have uncovered a possible method for eradicating HIV infection in the human body. The researchers have also revealed new information which demonstrates how HIV persists in the body - even in patients receiving drug treatments - and how the virus continues to replicate itself in individuals undergoing treatment. The research findings were published in the online version of the journal Nature Medicine on June 21 and will be featured in an upcoming print edition of the journal.
A new study analyzing the prevalence of sensory impairment among older U.S. workers found that hearing impairment prevalence was three times that of visual impairment, and that 38 percent of older workers reported experiencing either impairment.
Obesity is probably the most important factor in the development of insulin resistance, but science"s understanding of the chain of events is still spotty. Now, researchers at the Salk Institute for Biological Studies have filled in the gap and identified the missing link between the two. Their findings, to be published in the June 21, 2009 advance online edition of the journal Nature, explain how obesity sets the stage for diabetes and why thin people can become insulin-resistant.
Rearrangements of all sizes in genomes, genes and exons can result from a glitch in DNA copying that occurs when the process stalls at a critical point and then shifts to a different genetic template, duplicating and even triplicating genes or just shuffling or deleting part of the code within them, said researchers from Baylor College of Medicine in a recent report in the journal Nature Genetics. The report further elucidated the effect of the fork stalling and template switching mechanism involved in some forms of copy number variation.
Researchers at Brigham and Women"s Hospital and the University of Michigan
"Moving to a more continuous follow-up approach would have the tremendous advantages of enhancing patient safety, decreasing physician and nurse work load, and allowing health staff to focus on medical emergencies," urged Professor Angelo Auricchio, from the European Heart Rhythm Association (EHRA) and official spokesperson of the European Society of Cardiology (ESC), adding that such systems may have the additional advantage of being more cost effective for health care providers.
With an extensive, inoperable colon cancer and few options available, a Tennessee patient is seeing his cancer steadily regressing on a new outpatient treatment. Individuals from 26 U.S. states and four other countries have been among the first to use NeoPlas Innovation"s new protocol. The Tennessee patient"s early results mirror their successes in battling colon cancer and other very aggressive malignancies.
The fulfilment which so many people increasingly derive from competitive sports and endurance training comes with a real - even if rare - twist. Because, while most people will enjoy the benefits and pleasures of exercise, there are a few for whom regular athletic training will increase the risk of cardiac arrhythmias and even sudden death, especially among those in middle-age or with pre-existing cardiac diseases.
Merck & Co., Inc. said it supports a proposal to provide additional assistance to Medicare Part D beneficiaries who have reached the coverage gap (donut hole) in their prescription benefit.
As President Obama prepares to sign a bill giving the Food and Drug Administration (FDA) oversight of the tobacco industry, a new study from Harvard School of Public Health (HSPH) researchers shows that tobacco manufacturers have continually changed the ingredients and the design of their cigarettes over time, even if those changes have exceeded acceptable product variance guidelines. The result, say the researchers, is that consumers who buy the same brand of product are not made aware of how that product has been altered and what effect those alterations might have on their levels of addiction or harm.
When treating the diabetes patient, doctors discussed how a "one size fits all" approach to testing is not enough to reveal an individual"s risk for cardiovascular disease Saturday at the American Association of Clinical Endocrinologists (AACE) 18th Annual Meeting & Clinical Congress.
As President Obama prepares to sign a bill giving the Food and Drug Administration (FDA) oversight of the tobacco industry, a new study from Harvard School of Public Health (HSPH) researchers shows that tobacco manufacturers have continually changed the ingredients and the design of their cigarettes over time, even if those changes have exceeded acceptable product variance guidelines. The result, say the researchers, is that consumers who buy the same brand of product are not made aware of how that product has been altered and what effect those alterations might have on their levels of addiction or harm.
The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting exceptional early career researchers and innovative cancer research, named 17 new Damon Runyon Fellows at its May 2009 Fellowship Award Committee review. The recipients of this prestigious, three-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country. The Fellowship is specifically intended to encourage the nation"s most promising young scientists to pursue careers in cancer research by providing them with independent funding ($140,000 each) to work on innovative projects.
Psychology is the science of the mind and behavior. The word "psychology" comes from the Greek word psyche meaning "breath, spirit, soul", and the Greek word logia meaning the study of something. According to Medilexicon"s medical dictionary, psychology is "The profession (clinical psychology), scholarly discipline (academic psychology), and science (research psychology) concerned with the behavior of humans and animals, and related mental and physiologic processes." Although psychology may also include the study of the mind and behavior of animals, in this article psychology refers mainly to humans.
Oncothyreon Inc. (Nasdaq: ONTY) (TSX:ONY) (the "Company") announced that Merck KGaA of Darmstadt, Germany, has initiated a global Phase 3 trial of Stimuvax(R) (BLP25 liposome vaccine, L-BLP25) in patients with hormone receptor-positive, locally advanced, recurrent or metastatic breast cancer. Stimuvax is an investigational therapeutic cancer vaccine being developed by Merck KGaA under a license agreement with Oncothyreon.
Last week the FDA knocked the wind out of asthmatics by requesting the manufacturers of Singulair, a popular leukotriene blocking asthma and allergy drug, to upgrade their warning against psychotic side effects. Further respiratory distress was imposed on Zicam users when the FDA also last week announced warnings that the drug may cause a loss of smell.
Researchers at Children"s Hospital Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as a cancer treatment. Their findings were published in the online Early Edition of the Proceedings of the National Academy of Sciences during the week of June 22.
Scientists are focusing on a new concept in fighting airborne pathogens by manipulating what is called the "switching time," the point at which a highly regulated immune response gives way to powerful cells that specialize in fighting a specific invading bug.
Being overweight is a health concern, but Body Mass Index doesn"t tell the whole story because it is part of a larger picture, says a new advisory
Research at the University of Leicester is focussing on a major killer in UK hospitals. In England and Wales, the national health statistics in 2007 showed that there were 8,324 death certificates which named Clostridium difficile. This is a bacterium which causes severe diarrhoea in humans and animals as the underlying cause of death, a 28% increase from 2006.
A new study from the US suggests that the less socially active an older person is, the higher the chances that their motor ability such as strength
The American College of Obstetricians and Gynecologists (ACOG) has launched a new website devoted to women who are approaching or going through menopause to provide them with the necessary information they need to make informed decisions about their health. The ACOG-sponsored website can be found at http://pause.acog.org.
"No one can figure out a politically acceptable way to pay for an overhaul of America"s health care system, and until someone does, the effort is stalled. Maybe indefinitely," McClatchy reports. Michael Tanner, a "health care analyst" at the Cato Institute, says "it"s quite feasible that the whole thing could crash and burn because of sticker shock." The Senate Finance Committee has postponed writing legislation until July. "Legislative committees plan hearings and bill-writing sessions next week, and will face two key cost-related obstacles: No one really knows any plan"s price tag, and few so far are willing to take the political risk of raising taxes to pay for it. Add to that growing public wariness: Polls show people are increasingly disturbed by record federal deficits. A Wall Street Journal/NBC News poll conducted June 12 to 15 found that 58 percent said that the president and Congress should focus most on keeping the deficit down, even if that means it will take longer for the economy to recover."
Alabama"s summer climate with its extreme temperatures and high humidity can lead to heatrelated
Australia"s leading nutrition organisation, the Dietitians Association of Australia (DAA), has
CNN examines China"s efforts to curb the spread of HIV/AIDS by educating sex workers about the disease and prevention strategies. "It is estimated that some 700,000 people are living with HIV in China and there are about 50,000 new infections every year, according to the Chinese government and UNAIDS. The U.N. agency believes a significant number of those new infections include sex workers," CNN writes.
Instead of responding to natural disasters after they happen, aid should be dedicated to helping countries prepare for future disasters, John Holmes, the U.N."s emergency relief coordinator, said Friday, Reuters reports. "You can"t stop the disasters happening but you can make an enormous difference to whether they kill people and, to some extent at least, have their livelihoods destroyed," Holmes said during a press conference in Geneva that came at the end of a week-long meeting that tackled ideas on how to best prepare poorer countries for natural disasters.
Supreme Court nominee Sonia Sotomayor on Friday resigned from an all-women group in an effort to avoid claims that she belonged to a discriminatory organization, according to a letter she wrote to Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) and ranking member Jeff Sessions (R-Ala.), the Wall Street Journal reports. The group, the Belizean Grove, calls itself a "constellation of influential women" formed in response to the all-male Bohemian Club. Sotomayor wrote, "I believe the Belizean Grove does not practice invidious discrimination, and my membership did not violate the Judicial Code of Ethics, but I do not want questions about this to distract anyone from my qualifications and record." A Senate Republican aide said that GOP members did not plan to object to Sotomayor"s involvement in the group but aimed to compare their position with Democratic objections to previous judicial nominees who were members of all-male groups (Bravin, Wall Street Journal, 6/20).Sotomayor also sent Leahy and Sessions a list of events taken from her own handwritten calendar between 1992 and 1995, which included several entries about events where she spoke. Sessions had told Leahy that he would delay the confirmation proceedings if she did not provide missing information on about 50 speeches she had given. Sotomayor told the senators that she was unable to find drafts or recording of the speeches, noting that her calendar notes did not include details from the speeches (Swanson, The Hill, 6/19).In related news, the New York Times on Saturday examined how "it is far from clear that [Sotomayor"s] judicial record supports the accusation that she is an activist," who, as some critics have claimed, "legislates from the bench." According to the Times, "[s]everal empirical studies have concluded that she is not particularly prone to overriding policy decisions by elected branches." Her decisions that have "attracted the most criticism from conservatives" are "instances in which she deferred to policy decisions by elected branches that conservatives hoped judges would strike down," according to the Times (Savage, New York Times, 6/20).
Two studies recently published in the journal Nature Genetics report identifying new genes and gene regions that contribute to making people susceptible to developing MS. The findings, by the International Multiple Sclerosis Genetics Consortium and the Australia/New Zealand MS Genetics Consortium, add to a growing list of gene variations linked to MS susceptibility. Identifying all MS genes will likely lead to the development of more effective ways to treat the disease, and open the door to uncovering the cause of MS, which may lead to its prevention.
45th DIA Annual Meeting -- Booth # 1501 -- WorldCare Clinical, LLC (WCC), a leading imaging CRO for clinical trials in the pharmaceutical, biotechnology and medical device industries, announced that it is offering version 1.0 of the Metrics Champion Consortium (MCC) Imaging Performance Metrics to all sponsors" imaging trials beginning July 1, 2009, through its WorldPro™ technology solution.
Joel Drevet and colleagues, at Clermont Universitçİ, France, have identified a protein that helps protect immature mouse sperm after they have been released into a region of the testis known as the epididymis, which is where they undergo maturation. Although male mice lacking this protein, Gpx5, had normal looking sperm and were equally as efficient as normal male mice at fertilizing female mice, an increased incidence of miscarriages and fetal developmental defects were observed when normal female mice were mated with Gpx5-deficient males over 1 year old compared with normal male mice of the same age. Further analysis indicated that Gpx5 acts as an antioxidant in the epididymis, protecting the sperm from oxidative stress. As discussed by the authors, and, in an accompanying commentary, John Aitken, at the University of Newcastle, Australia, these data have immense clinical relevance as age-related DNA damage to human sperm has been associated with a range of adverse outcomes including decreased fertility, and increased rates of miscarriage and childhood disease.
Neovacs, a biotechnology company developing proprietary immunotherapeutics for autoimmune and chronic diseases, announced that subject to regulatory consent, it plans to initiate a Phase II study of its TNF-alpha Kinoid later this year in rheumatoid arthritis patients who have failed treatment with at least one TNF-alpha inhibitor. The decision to proceed with the trial was based on an initial review of encouraging data from the company"s Phase I/II study in Crohn"s disease.
An immediate overhaul of the Department of Veterans Affairs disability claims processing system is the only way out of a fast-growing nationwide backlog of unresolved cases, American Legion National Commander David K. Rehbein said after a congressional hearing last Thursday evening.
A global healthcare senior executive has called the latest infection threat to confront the NHS "a national epidemic". Whilst Government statements imply that hospital acquired infections are in decline Jim Taylor, a former Smith & Nephew President and now CEO of infection prevention specialist Saniguard International, says that Norovirus is now an increasing threat to our NHS wards. His company is launching PatientGuard this month - an anti-infection kit created specifically for the UK public, designed to help halt the spread of viruses (including Norovirus & H1N1) & bacteria (including MRSA).
Only 37, Janie Lee had endured excruciating back pain for 20 years. She couldn"t stay in one position for more than five minutes, and walking hunched over was the only way she could get around. Her search for help took her to several doctors and an emergency room, but it wasn"t until she found Hyun Bae, M.D., a renowned spine specialist at Saint John"s Health Center in Santa Monica that she received the diagnosis and care that would return her life to her.
Today, President Obama took historic action to save lives, reduce health care costs, and help reduce suffering from heart and lung diseases, cancer, and other tobacco-related illnesses. These illnesses kill hundreds of thousands of Americans every year, and the new law gives us the tools to effectively address this major public health issue. This is a key step forward and an important part of health reform.
Telecoms, healthcare and display technology will be the major beneficiaries of a new generation of semiconductor lasers developed in a massive European research effort. Better cancer treatment, wider bandwidth and smaller, better displays could be on their way.
Primary care clinicians and their staff appear to fail to inform some patients, or to fail to document informing patients, about abnormal results on outpatient medical tests, according to a report in the June 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Greater influence over everyday life, emotional support, and cultural and recreational activities help to enable teenage girls to withstand stress. Those were the results of a dissertation from the Sahlgrenska Academy, University of Gothenburg, Sweden.
Health workers fail to understand the importance of sex for Tanzanian children
The American Cancer Society and the National Palliative Care Research Center (NPCRC) are awarding $1.5 million in research grants to researchers at eleven institutions for studies aimed at reducing suffering for seriously ill patients and their family caregivers. The studies will be conducted over the next two years. The NPCRC, in collaboration with the American Cancer Society, has directed over $5 million towards supporting 38 palliative care research projects since starting this initiative three years ago.
HealthLeaders-InterStudy, a leading provider of managed care market intelligence, reports that while health systems and physician groups in the Phoenix market seem to be ahead of the curve in adopting electronic medical records (EMR), there is a high rate of "deinstallation" wherein physician groups cancel their EMR contracts as a result of training, functionality or affordability issues. According to the recent Phoenix Market Overview, this trend is especially prevalent among smaller physician groups and points to the need for a simplified, affordable solution.
A study that attempted to replicate the "seminal" study that laid the
BMA Scotland has warned that children who smoke face years of tobacco addiction that can lead to life-threatening diseases and premature death. The association also called on MSPs to support the proposals contained in the Tobacco and Primary Medical services (Scotland) Bill in order to reduce children"s exposure to tobacco products.
Alabama"s summer climate with its extreme temperatures and high humidity can lead to heatrelated
The Maine Center for Disease Control and Prevention of the Maine Department of Health and Human Services, is issuing an advisory about the danger of carbon monoxide poisoning when people open camps for the summer.
The California Medical Association applauded the U.S. Senate Finance Committee for producing a thoughtful analysis of ways to expand the nation"s health care coverage. The committee"s paper, titled "Expanding Health Care Coverage: Proposals to Provide Affordable Coverage to All Americans," includes certain market reforms that all participating health plans would be required to participate in.
President Obama is causing the "core culture-war battle" over sex education to "come full circle" by proposing to redirect funding for abstinence-only sex education to a new Teen Pregnancy Prevention Initiative that "rejects an abstinence-only approach," Washington Times columnist Cheryl Wetzstein writes. According to Wetzstein, Obama"s fiscal year 2010 budget plan "zeroed out" the Title V abstinence-only sex education grant program, set to expire on June 30, and the Community-Based Abstinence Education program. Wetzstein continues that groups supporting comprehensive sex education have "loathed Title V from its inception" because of its "prohibition on teaching teens how to use birth-control products (i.e., no condom demonstrations) and its eight-point definition that seemed utterly unrealistic to sex educators." For example, Title V"s definition said that the ""expected standard of human sexual activity"" was a ""mutually faithful, monogamous relationship in the context of marriage,"" which Wetzstein says she has "heard many times, was insulting to gay youth who couldn"t marry" and "insensitive to minority youth who grew up in neighborhoods where marriage was rare." Wetzstein asks, "What will happen to Title V?" She writes that opponents "are staying vigilant" and working to avoid "any last-minute, back-door revivals of this program." Groups that support abstinence-only sex education are "working the phones, too," Wetzstein reports. According to Wetzstein, Valerie Huber, executive director of the National Abstinence Education Association, noted that "[s]aving Title V will require some heavy lifting, but "it"s expired before and been retroactively renewed."" Wetzstein concludes that "we"ll soon see what happens with the new players in town" (Wetzstein, Washington Times, 6/23).
The Allied Health Professions Leadership Challenge winners are East Midlands SHA, The Department of Health announced today.
While Ontario women live longer than men, a majority are more likely to suffer from disability and chronic conditions, according to a new women"s health study by St. Michael"s Hospital researcher Dr. Arlene Bierman. What"s more, low-income women have more chronic conditions, greater disability and a shorter life expectancy than women in high-income groups.
Leaders of the major faith groups have put their support behind the Wall of Life, an interactive campaign launched today by NHS Blood and Transplant (NHSBT). The campaign - at http://www.walloflife.org.uk - aims to promote awareness of and support for organ donation to boost the number of people joining the NHS Organ Donor Register (ODR).
The AOAC Research Institute, the approval body for all U.S. food safety tests, has certified Vacci-Test"s FoodChekTM-E.Coli as a Performance Tested(SM) method for detecting E.coli O157 in raw ground beef. This extremely rapid and accurate new test is seen as a technological breakthrough for meat-processors. This approval clears the way for FoodChekTM-E.Coli to be sold as a certified food safety test in the United States and internationally.
MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) today announced that the Company has submitted an application for the authorization of a phase 1b/2a clinical study in patients with active rheumatoid arthritis (RA) for its lead drug MOR103, a fully human HuCAL-derived monoclonal antibody directed against Granulocyte Macrophage-Colony Stimulating Factor. The trial, which will be conducted in multiple centers in several European countries, is expected to enroll 135 patients in total beginning in the second half of 2009. Additionally, the Company today reported positive results from the phase 1 clinical study for MOR103 in healthy volunteers. The results of this study indicate that MOR103 is generally safe and well tolerated at all doses administered.
New research indicates that a finding on a routine electrocardiogram that signals a disorder of the electrical conducting system in one part of the heart and previously believed to be benign is associated with an increased risk for atrial fibrillation, the implantation of a pacemaker or death, according to a study in the June 24 issue of JAMA.
Dr. Janet D. Latner, an Associate Professor of Psychology at the University of Hawai"i at Manoa, has co-authored an article in the July 2009 edition of the Journal of Sex & Marital Therapy on "Weight Stigma in Existing Relationships."
A US doctor who diagnosed and treated herself for breast cancer while stationed in the South Pole during the winter of 1999, was then rescued
Exercise has many benefits from improving cardiovascular capacity to reducing weight, and now a new
Atrial fibrillation (AF) is the most common arrhythmia, affecting an estimated 7 million people worldwide, including 4.5 million in the European Union1,2. Data presented today as a Hot Line session at the EUROPACE 2009 congress on the XPECT clinical trial, sponsored by Medtronic, Inc. (NYSE: MDT), shows that the Medtronic Reveal® XT Insertable Cardiac Monitor (ICM) reliably identifies patients with AF (sensitivity of 96.1 percent) and correctly confirms the absence of AF in patients (negative predictive value of 97.4 percent).
Compugen Ltd. (NASDAQ:CGEN) announced that CGEN-25007, a novel peptide antagonist of gp96 with potent anti-inflammatory activity, has shown positive therapeutic effects in an animal model of inflammatory bowel disease (IBD), a commonly used term covering ulcerative colitis and Crohn"s disease.
Hospitals could sign on to an agreement with Senate health reform leader Max Baucus, D-Mont., and the White House to help save up to $200 billion as part of the overhaul plan, lobbyist and health industry s tell Roll Call. The possible deal would come on the heels of an agreement between the drug industry lobbying group, Pharmaceutical Research and Manufacturers of America and senior Democrats to save $80 billion over 10 years by expanding the Medicare drug program. The American Hospital Association, the Federation of American Hospitals and the Catholic Health Association are all said to be in talks about the potential bargain.
Figures from the British Institute for Anger Management reveal that the UK already has the worst road rage figures of any European nation, with 80% of drivers saying they"ve been involved in an incident and 1 in 4 admitting to committing an act of road rage themselves. Men are three times more likely to commit an act of aggression than women and over 60% of drivers say they have been intimidated by aggressive tailgating.
Fear, religious beliefs and cultural differences are among the reasons why blacks do not get tested for HIV, participants of the National Baptist Convention USA"s annual Congress of Christian Education conference being held in Detroit, said on Monday, the Detroit Free Press reports. As part of the five-day conference, religious leaders discussed ways to address the high rates of HIV and AIDS among the black community. Participants also said that concerns of racism by medical professionals may be a reason why blacks do not get tested. Simone Phillips of the St. Louis chapter of the American Red Cross said, "A lot of people are leery" in the black community and "we [need] to get rid of the stigma" surrounding HIV/AIDS (Warikoo, Detroit Free Press, 6/23).
There was more than a 50 percent drop in the total number of malaria cases reported by public facilities in Cambodia between 2003 and 2008, according to the National Centre for Parasitology, Entomology and Malaria Control"s annual report, which was released on Tuesday, the Phnom Penh Post reports. Officials are attributing the decrease to village-based treatment and education programs.
The Rheumatology Futures Project and the Department of Health have launched a new 18-week commissioning pathway for inflammatory arthritis (IA).
President Richard Nixon, who was in office when the Supreme Court issued its 1973 decision in Roe v. Wade, in secret recordings from January and February of that year discussed his views on abortion with an aide, the New York Times reports. The comments were among more than 150 hours of tape and 30,000 pages of documents made public Tuesday by the National Archives" Nixon Presidential Library. The tapes were recorded by secret microphones in the White House"s Oval Office. Nixon in the tapes expressed ambivalence over the decision, as well as concern that increased access to abortion leads to "permissiveness" and that "it breaks the family." Nixon also said that he believed there was a need for abortion in some cases, including interracial pregnancies and rape. He said, "There are times when an abortion is necessary. I know that." He added, "When you have a black and a white. Or a rape" (Savage, New York Times, 6/24).Broadcast CoverageNPR"s "All Things Considered" on Tuesday reported on Nixon"s abortion comments and political reaction to Roe at the time of the decision (Totenberg, "All Things Considered," NPR, 6/23).
Although it is "important for other young people to hear" Bristol Palin"s message "about how hard it is to be a teenage mother," her "lesson falls short by suggesting that any teen can successfully avoid premarital sex," a Philadelphia Inquirer editorial says. Palin, who gave birth in December 2008 after an unintended pregnancy and is the daughter of Alaska Gov. Sarah Palin (R), has "changed her tune" since she said in a February interview that teen abstinence is ""not realistic at all,"" the editorial states. It adds that Bristol Palin -- now an "abstinence ambassador" for the Candie"s Foundation -- recently said that abstinence is "realistic" and that it is the "harder choice, but it"s the safer choice."The editorial continues that Palin is correct that "[a]bstinence is the only foolproof way to avoid pregnancy" and sexually transmitted infections. However, "any viable lesson about avoiding teen pregnancy should include methods besides avoiding sex, including the use of condoms," the editorial says. Recent studies have shown that abstinence-only sex education programs have had "no measurable impact on delaying teens from having sex for the first time," according to the editorial, which adds that teen pregnancy rates rose 5% between 2005 and 2007 after years of declines. Additionally, three out of 10 U.S. girls will get pregnant by age 20, a figure that increases to more than 50% for Hispanics and blacks. The editorial concludes that teens "need frank talk about premarital sex that includes all of the viable options to avoid pregnancy" (Philadelphia Inquirer, 5/15).
County public health officials in California say proposed budget cuts could hurt or end the state"s Maternal, Child and Adolescent Health Program, which provides care for high-risk women and teenagers during pregnancy and up to one year after giving birth, the Riverside Press-Enterprise reports. County health departments operate the program with oversight from the state Department of Public Health. Sarah Mack, a spokesperson for the Riverside County Department of Public Health, said the program provides a safety net for women who are uncertain about how to obtain prenatal care. The program"s nurses and social workers work to identify vulnerable groups with the goal of initiating care within the first trimester of pregnancy. The program aims to reduce incidences of low birthweight, premature delivery, maternal and infant mortality, preventable childhood diseases and disabling conditions.Gov. Arnold Schwarzenegger (R) has proposed eliminating more than $20 million in funding from the program to help reduce California"s estimated $24 billion budget deficit. Last week, the state Legislature"s joint budget conference introduced a counterproposal that would lower cuts to the program to $8 million.The most recent statistics from the state public health department show that nearly 16,000 California women who gave birth in 2006 had late or no prenatal care. More than 38,500 low-birthweight infants were born that year. Jim Lindley, director of the San Bernardino County Department of Public Health, said that Schwarzenegger"s proposal would amount to the elimination of "the bulk of funding" for the program. Mack said that Riverside County officials have identified scenarios to continue providing services if the state funding is eliminated. However, without the funding, "[m]ore people could fall through the safety net," Mack said, adding, "Those who need the program the most would be the most likely to fall through."Schwarzenegger spokesperson Lisa Page has said that the governor believes the state"s budget situation leaves him with little choice about making cuts (Hines, Riverside Press-Enterprise, 6/22).
The National Association of Chain Drug Stores (NACDS) today announced that the 2009 NACDS Pharmacy & Technology Conference will provide a forum at which to provide further recognition to Leonard J. DeMino, RPh., a chain pharmacy icon whose resume already includes some of the industry"s highest honors and achievements. This news comes as DeMino announces his retirement as senior pharmacy consultant to NACDS, effective in June 2009.
Researchers led by Drs. James F. George and Anupam Agarwal at the University of Alabama at Birmingham have found that carbon monoxide (CO) can protect against arterial clotting. They report their data in the July 2009 issue of the American Journal of Pathology.
Current research suggests that levels of gastrin play a key role in the development of Helicobacter-induced stomach cancer. The related report by Takaishi et al, "Gastrin is an essential cofactor for Helicobacter-associated gastric corpus carcinogenesis in C57BL/6 mice," appears in the July 2009 issue of The American Journal of Pathology.
Although there is no doubt that hypnosis can impact the mind and behavior, the underlying brain mechanisms are not well understood. Now, new research provides fascinating insight into the specific neural effect of the power of suggestion. The study, published by Cell Press in the June 25 issue of the journal Neuron, uncovers the influence of hypnotic paralysis on brain networks involved in internal representations and self imagery.
The Welsh Assembly Government is today encouraging people to nominate health professionals for a major UK-wide award aimed at highlighting their contribution to the care of armed services personnel.
South London Healthcare NHS Trust (SLHT) is delighted to announce a new partnership with the NHS Institute for Innovation and Improvement as part of the trust"s drive for
The first clinical trial funded by the new Efficacy and Mechanism Evaluation (EME) programme will investigate whether a simple procedure to activate one of the body"s natural defence mechanisms improves the function of kidneys after transplantation. This research is funded by the Medical Research Council and managed by the National Institute for Health Research.
Kidney injury that can arise after undergoing certain medical imaging procedures increases a patient"s risk of having a stroke or heart attack over the next year or two, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The findings indicate that seemingly minor and reversible kidney damage from these common clinical procedures is a serious health threat.
The American Thoracic Society and the European Respiratory Society have released official standards for clinical trials and practice with respect to the assessment of asthma. The statement appears in the July 1 issue of the American Journal of Respiratory and Critical Care Medicine.
Some patients with large tumors on their larynx can preserve their speech by opting for chemotherapy and radiation over surgery to remove the voice box.
Each year, approximately 795,000 people experience a new or recurrent stroke1 in the United States, and approximately a half million people in Western Europe are similarly afflicted2. Today, Medtronic, Inc. (NYSE: MDT) announces two significant clinical trials related to medical device interventions for stroke. First enrollments in the global CRYSTAL AF (Study of Continuous Cardiac Monitoring to Assess Atrial Fibrillation After Cryptogenic Stroke) trial have taken place. The trial will use the Reveal® XT Insertable Cardiac Monitor (ICM) to assess the incidence of atrial fibrillation (AF) in patients with cryptogenic stroke (stroke of an undetermined cause) or transient ischemic attack (TIA) in order to aid physicians in determining the optimal course of treatment for these patients. It is widely recognized that patients with sustained AF are at increased risk of stroke3.